| BRIEF COMMUNICATION |
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| Year : 2016 | Volume
: 2
| Issue : 4 | Page : 229-232 |
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The Consistencies of Y-Chromosomal and Autosomal Continental Ancestry Varying among Haplogroups
Chuan-Chao Wang1, Lei Shang2, Hui-Yuan Yeh3, Lan-Hai Wei4
1 Department of Genetics, Harvard Medical School, Boston, MA, USA; Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany
2 Key Laboratory of Forensic Genetics, Institute of Forensic Science, Ministry of Public Security, Beijing, China
3 School of Humanities and Social Sciences, Nanyang Technological University, Singapore
4 State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China
Correspondence Address:
Chuan-Chao Wang
Department of Genetics, Harvard Medical School, Boston, MA, USA; Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2349-5014.197925
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The Y-chromosome has been widely used in ancestry inference based on its region-specific haplogroup distributions. However, there is always a debate on how informative such a single marker is for inferring an individual's genetic ancestry. Here, we compared genetic ancestry inferences at continental level made by Y-chromosomal haplogroups to those made by autosomal single-nucleotide polymorphisms in 1230 samples of Affymetrix Human Origins dataset. The highest ancestry proportions of a majority of individuals match the highest average continental-ancestry proportions in haplogroups A, B, D, H, I, K, L, T, O, and M. The high consistencies have not been observed in haplogroups E, C, G, J, N, Q, and R, but in some of their sublineages, such as E1a, E1b1a1, E1b1b1b1a, E2b1a, J1a2b, Q1a1a1, Q1a2a1a1, R1b1a2a1a, and R2. Although the consistencies of Y-chromosomal and autosomal continental ancestry vary among haplogroups, Y-chromosome could provide valuable clues for individual's continental ancestry. |
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