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  Indian J Med Microbiol
 

Figure 1: Hematoxylin- and eosin-stained sections of the cerebral cortex showed two general abnormalities in those cases with pathological alterations. Changes in transient global ischemia (a; scale bar = 100 μm) with eosinophilic neurons and diffuse cytotoxic edema were observed in a subset of cases. This change is a secondary event, requiring regional ischemia followed by resuscitation and some period of survival (4–6 h or more). Other cases showed distinct perivascular vacuolation (b; circles indicate cortical blood vessels; scale bar = 200 μm), or vasogenic edema, without features of transient global ischemia

Figure 1: Hematoxylin- and eosin-stained sections of the cerebral cortex showed two general abnormalities in those cases with pathological alterations. Changes in transient global ischemia (a; scale bar = 100 μm) with eosinophilic neurons and diffuse cytotoxic edema were observed in a subset of cases. This change is a secondary event, requiring regional ischemia followed by resuscitation and some period of survival (4–6 h or more). Other cases showed distinct perivascular vacuolation (b; circles indicate cortical blood vessels; scale bar = 200 μm), or vasogenic edema, without features of transient global ischemia